Accessing Ensembl Regulatory Annotation

Regulation data in Ensembl can be accessed through:

• The Ensembl Browser (see below)
• Ensembl FTP
• BioMart (Ensembl Regulation database).

Browser access

Location Tab

You can configure the Region in detail panel to display tracks linked to regulation. The Regulation tracks are grouped into subdivisions:

• Regulatory Features: these can be visualised using the 'Regulatory features' track.
• Activity by Cell/Tissue: select the tissue or cell type (epigenome) of interest to display peaks, signal and regulatory feature activity across the genome.
• Other regulatory regions: imported tracks from external databases.

Gene tab

Click on the Regulation link in the left hand side menu to view the regulatory features and eQTLs in the vicinity of your gene.

Regulation tab

Clicking on a regulatory feature will open a Regulation tab with information about the evidence supporting that regulatory feature as well as cell-specific activity estimates. Different views can be selected:

• Activity: this view displays the selected regulatory feature and a summary of its regulatory activity across cell types.
• Source Data: this view displays the list of source data for the chosen regulatory feature.